Child Observational Development (ChiDO) Study

Child Observational Development (ChiDO) Study

The Child Observational Development (ChiDO) Study is a prospective cohort study following ~600 infants across the developmental delay and neurodevelopmental impairment (DD/NDI) risk spectrum related to perinatal asphyxia/neonatal encephalopathy in Harare, Zimbabwe. Aim 1 is to evaluate the validity of several neurodevelopmental assessment tools, including the Prechtl General Movement Assessment (GMA) and the Hammersmith Infant Neurologic Examination (HINE). Both have shown high sensitivity and specificity for cerebral palsy and cognitive delays, but have limited validation in LMICs. This study will also preliminarily evaluate the Global Scales for Early Development (GSED), which were created as validated developmental assessment instruments for population-level and programmatic evaluation of children ages 0 to 3 years from culturally, linguistically and socioeconomically diverse populations. The ChiDO study will be the first to validate GSED’s use for individual-level assessment.

Collaborators

Susanne Martin Herz

MNCH Title
Professor
Primary Affiliation
University of California San Francisco

Louisa Mudawarima

MNCH Title
Pediatrician; Lecturer
Primary Affiliation
University of Zimbabwe Medicine and Health Sciences

Gwendoline Chimhini

MNCH Title
Pediatrician; Senior Lecturer
Primary Affiliation
University of Zimbabwe Medicine and Health Sciences

Hilda Angela Mujuru

MNCH Title
Professor
Primary Affiliation
University of Zimbabwe Medicine and Health Sciences

Nicole Santos

MNCH Title
Research and Program Manager
Primary Affiliation
University of California San Francisco

Rakesh Ghosh

MNCH Title
Biostatistician & Epidemiologist
Primary Affiliation
University of California San Francisco
Funder
Thrasher logo
Key Partners
University of Zimbabwe